http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1785729-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2006-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76443f9dda85c9177125c8c795281dbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6bb6d95ff1b11fae0c6f771d6f3188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4c76f1056d05971d51cf9a05ccf9ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3486655c0b9ee181e84eac0fddbfe217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dec48c99bac05b454c8e8f6c9a76b888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f61c29921bb630961c334cf2bb6317d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c7ffe64b4e4aa864b2f50f631c56aac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaa410bf002d7be475ab4f379fbdf665 |
| publicationDate | 2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1785729-A3 |
| titleOfInvention | A method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics |
| abstract | The present invention describes a method that combines the blocking of primary amino groups and the cation exchange chromatography, to simplify peptide mixtures that can be generated or not by proteolytic or chemical treatments. This method allows the selective isolation of an average of 4 multiply-charged peptides (RH peptides) per protein and the study of 90% of the proteins of the analyzed proteomes. It is applicable to studies of quantitative proteomics without the usage of two-dimensional electrophorsis, it is compatible with any type of isotopic labeling and it is very useful to determine the differential expression of proteins present in multiple conditions (3 to 6 conditions) when using different isotopic labeling in a single experiment. The chromatographic system used also allows the fractionation fraction of the RH peptides to achieve the identification of a greater number of proteins. |
| priorityDate | 2005-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005176085-A1 |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458396401 |
Total number of triples: 22.