http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005170435-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4719 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 |
| filingDate | 2004-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2928b401257f90df43218ce5336793f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2110dbc0bf3c38b45cf3aa69a1e3a28e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9590933b27f155c117f0df7617145baa |
| publicationDate | 2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005170435-A1 |
| titleOfInvention | Biosensor and use thereof to identify therapeutic drug molecules and molecules binding orphan receptors |
| abstract | A G protein biosensor cell comprises G protein beta, gamma or both beta and gamma subunits tagged with a fluorescent protein(s) expressed in living intact functional cells. The subcellular location of the fluorescent protein tagged beta, gamma or both beta and gamma subunits is strongly responsive to the activation state of specific G protein coupled receptors in the biosensor cell. The biosensor cell responds reproducibly to agonist and antagonist drug molecules specific for G protein coupled receptors by demonstrating translocation of the fluorescent protein tagged beta, gamma or both beta and gamma subunits from one part of the cell to another. The biosensor cells have utility in identifying and classifying candidate therapeutic drugs as to their therapeutic value. |
| priorityDate | 2004-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 332.