| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4719 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 |
| filingDate |
2001-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2231ea14b83d9211bb0bcee8996f9266
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef6990cfa5bbd69037f4ca820fd3ab6 |
| publicationDate |
2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2002048811-A1 |
| titleOfInvention |
Receptor mediated activation of heterotrimeric G-proteins |
| abstract |
Receptor mediated activation of heterotrimeric G-proteins is visualized in living cells by monitoring fluorescence resonance energy transfer (FRET) between subunits of a G protein fused to cyan and yellow fluorescent proteins. The G-protein heterotrimer rapidly dissociates and reassociates upon addition and removal of cognate ligand. Energy transfer pairs of G-proteins enables direct in situ detection and have applications for drug screening and GPCR de-orphaning. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2375240-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8647887-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10458993-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2010207880-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004072608-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005170435-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1532445-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006099643-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1532445-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8580517-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013179062-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104350383-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007190656-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006110732-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004072608-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013179062-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8084575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004224361-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006272037-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010085844-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2856161-B1 |
| priorityDate |
2000-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |