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publicationDate 2005-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2005019303-A1
titleOfInvention Biodegradable copolymer, and polymeric micelle composition containing the same
abstract A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.
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