| abstract |
The present invention relates to polyethyleneglycol/polylactide (or polyglycolide or polycaprolactone)/polyethyleneglycol triblock copolymers with an enhanced reactivity, and process for their preparation. n More specifically, the present invention is directed to triblock copolymers that are obtained by the process comprising the step of synthesizing a polylactide (or polyglycolide or polycaprolactone) having hydroxy groups at both ends and the step of coupling said polylactide with polyethyleneglycol having an acylhalide group of a high reactivity at one of its ends, and the process for preparing the same. n Since the triblock copolymer according to the present invention has an ester structure with good biocompatibility, it can be applied extensively for biomaterials used in tissue engineering, in a matrix that slowly releases drugs, etc. |