| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4718
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2004-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee0c098ff09f3781c3645984d647c38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b99e837de1b602ccd92ab4b68e71274
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f5f32b142b3ee6816543aa796cbf6d7 |
| publicationDate |
2004-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004166538-A1 |
| titleOfInvention |
Reversed mammalian protein-protein interaction trap |
| abstract |
The present invention relates to a recombinant receptor, comprising a ligand-binding domain and a signaling domain that comprises a heterologous bait polypeptide, which receptor is inactivated by binding of a prey polypeptide to the heterologous bait peptide, either in presence or absence of a ligand binding to the ligand-binding domain. The receptor is activated by addition of a compound that disrupts the bait-prey interaction. The present invention also relates to a method of screening compounds that disrupt compound-compound-binding using the recombinant receptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10641765-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10379115-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11231416-B2 |
| priorityDate |
2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |