| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
| filingDate |
2003-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ac7c1898a16a6b7f04889bc5a7cb1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad381c69887200ab6c24c032db4cd1d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_746786d9efda83a312f18219d8fe16d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b49cafbac09095765d89c8f87fd5934
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d6b7d1fbcffc59d9733719000c8ff9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecf3b1610d35b90c8da1045ffb4c9b13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_319bc16e18b2f0e7be2b05452b184827 |
| publicationDate |
2004-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004087775-A1 |
| titleOfInvention |
Process for production diphtheria toxin |
| abstract |
The present invention provides a method of purifying diphtheria toxin comprising (1) fermenting a microorganism strain capable of producing diphtheria toxin using glucose as a carbon source, said method comprising adding glucose to a growing culture whereby the addition of glucose maintains microorganism growth effective to support diphtheria toxin production; and (2) purifying the diphtheria toxin from the culture by contacting a toxin containing preparation derived therefrom with an ion exchange matrix, eluting a fraction containing the toxin, applying the eluate to a hydrophobic matrix, and eluting a fraction containing the toxin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2495341-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9040058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009136827-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2495341-A |
| priorityDate |
1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |