http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002115866-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44367c7b17bf07d2d403f117a3fe1a97 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34 |
| filingDate | 2001-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_320bf390be1c31d3c48b9a5908c05347 |
| publicationDate | 2002-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2002115866-A1 |
| titleOfInvention | Process for the preparation of pyridine derivative |
| abstract | The invention discloses a process for the preparation of a pyridine derivative namely 5-{4-2(N-methyl-N(2-pyridyl) amino ethoxy]benzyl]thiazolidine-2,4-dione maleate comprising the steps of: n (a) reacting 2-chloropyridine with 2-(N-methyl amino) ethanol; n (b) coupling 2-N-methyl-N-(2-pyridyl)amino)ethanol) obtained in step (a) and 4-fluorobenzaldehyde in an aprotic polar solvent with an alkali metal hydroxide or an alkali metal alkoxide as base. n (c) isolating the product of the coupling reaction viz 4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzaldehyde; n (d) converting said isolated benzaldehyde compound of step (c) into 5-[4-[2-N-methyl-N-(2-pyridyl) amino)ethoxy]benzyl]thiazolidine-2,4-dione in a known manner and n (e) converting said thiazolidine-2,4-dione compound obtained in step (d) into a pharmaceutically acceptable maleate salt. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010081695-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632841-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009270630-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005043539-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007293546-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007265313-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7435741-B2 |
| priorityDate | 2000-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.