| abstract |
According to the present invention, effervescent controlled release water soluble or swellable hot-melt extruded films are provided. Such films comprise a hot-melt extrudable water soluble or swellable binder, an active ingredient, an effervescent couple and optionally another compound such as a plasticizer. The films are made by a hot-melt extrusion process. Bioadhesive effervescent films can also be made by the invention. |