Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bfdf49224a405be1f7b653c56ebad94 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
filingDate |
2018-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97957bc570cca8ce1f17bd9eff65ca48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f78143fe8a91324cae43dca50f7274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca9ac94897ad936cdc5d6dcda4132fbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9638f67a8ebdf5d64f209050fd76ff72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a008b75e8c7a9ecd92b829cbf58199d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9a9f7b9560e2fbf7eb5b68455ad2bbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab26845e95aa0afe5742fd36f57f4f50 |
publicationDate |
2023-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11542301-B2 |
titleOfInvention |
Fc-binding protein having improved antibody separation ability, and method for separating antibody using same |
abstract |
The present application addresses the problem of providing an Fc-binding protein having an improved antibody separation ability. The present application also addresses the problem of providing a high-accuracy antibody separation method using an insoluble carrier having the protein immobilized thereon. The problems can be solved by: an Fc-binding protein in which at least an amino acid substitution at a specific position therein occurs and which has reduced affinity for an antibody; and an antibody separation method including allowing an equilibration buffer solution to pass through a column in which an insoluble carrier having the protein immobilized thereon is filled to equilibrate the column, adding a solution containing an antibody to cause the adsorption of the antibody onto the carrier, and eluting the antibody adsorbed on the carrier using an elution solution. |
priorityDate |
2017-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |