| abstract |
The present invention provides an Fc-binding protein having improved stability of an Fc-binding protein, particularly stability against heat and acid, a method for producing the protein, and an antibody adsorbent using the protein. An Fc-binding protein having improved stability against heat and acid by substituting an amino acid residue at a specific position in an extracellular region with another specific amino acid in human FcγRIIIa, The above problems are solved by a production method and an antibody adsorbent using the protein. [Selection] Figure 5 |