Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e59372b330374bf4bfee2c1cfd3dc54b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-64 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
filingDate |
2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea1b143d35534fa8a57f187b371a177a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_897c8de52425c9bb369bc8a7026b0f3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52eb2e368dd83aa019c9f1b70d8c59d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_282cd712e8974c69757ea41ec61ca3a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2587b0ceaf96fec736357d8b2a7c3a10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9866ada5ee312afdf21c1df4119602a1 |
publicationDate |
2022-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11311605-B2 |
titleOfInvention |
Methods of treating heart failure and fibrotic disorders using modified relaxin polypeptides |
abstract |
Modified relaxin polypeptides and their uses thereof are provided. Exemplary embodiments provide relaxin polypeptides which include one or more amino acid substitutions with natural or non-naturally encoded amino acids, and/or linkage to a water-soluble polymer, such as polyethylene glycol. Additionally, use of said relaxin polypeptides for treatment of disease, such as heart failure, is also provided. |
priorityDate |
2010-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |