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filingDate 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11135214-B2
titleOfInvention Methods for enhancing the bio availability and exposure of a voltage-gated potassium channel opener
abstract In certain embodiments, the present disclosure is directed to methods and uses for treating seizure disorders in a human, wherein the methods and uses comprise orally administering a therapeutically effective amount of the voltage-gated potassium channel allosteric modulator, N-[4-(6-fluoro-3,4-dihydro-1H-isoquinolin-2-yl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide (Compound A), to the human in need thereof, for example, under fed conditions. The present disclosure is further directed to various improved methods of therapy and administration of Compound A.
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