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filingDate 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11022614-B2
titleOfInvention Antibodies binding to trimeric TNF alpha epitopes
abstract It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO02765
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16071
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID453
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID66674260
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID395083
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280845
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID442859
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415826292
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21948
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25069
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID117516
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4049
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4982
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41155
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2194
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25341
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP09225
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226393819
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394420
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100151629
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID442968
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID8060
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID395385
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ862Z7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP01374
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ06643
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100270764
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID338033
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO00300
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID514239
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5798
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3ZDR4
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3355111
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID58026787
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID22164
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID22163
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID668542
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10095
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID498666
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID246097
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102723407
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21943
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID407742
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID407674
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8600
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID282387
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8744
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP10154
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21942
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO55237
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8742
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21941
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33524
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5366546
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395153
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395152
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID789154
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9XT48
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21944
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID54684461
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6251
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID117361
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16994
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID1476581
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID245527
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID513836
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16992
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID407111
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID1476581
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID28421
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8764
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21948
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226393712
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID500598
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102724971
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100037357
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID84957
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8794
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5TM22
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID733577
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID735295
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8792
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100535903
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21947
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395405
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID36521
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9JM09
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419589026
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395404
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5TM20
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID793819
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1896
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID560966
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID36514
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ06332
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID554305
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394880
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8784
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID461406
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403634
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21950
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41274
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID107428
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21949
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID171369
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID10673
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID31364
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7133
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID320100
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19147
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID9966
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7132
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID397395
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID565756

Total number of triples: 406.