| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0219
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-824
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-233 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2226
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-42 |
| filingDate |
2018-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47287e03ec4e011f0481d7cd8905bbbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53b4e4d91d01909926865f7cb26f213 |
| publicationDate |
2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10875822-B2 |
| titleOfInvention |
Directed β-C(sp3)#H iodination and arylation of ketones |
| abstract |
This invention discloses the first example of palladium(II)-catalyzed β-C(sp 3 )-H iodination or arylation of a wide range of ketones by using a commercially available aminooxyacetic acid auxiliary. This L, X-type directing group overcomes the limitation of the transient directing group approach for -βC(sp 3 )-H functionalization of ketones. Practical advantages of this method include simple installation of the auxiliary without chromatography, exceptional tolerance of a-functional groups, double bonds and triple bonds and rapid access to diverse sterically hindered quaternary centers. |
| priorityDate |
2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |