| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c41841dac6c2b902e5a048729328b1e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d91a0cb4f89dddd6971af61728d88ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46729a6e12e81f1603ba14c15b5920dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc130796935dde705b214b043ad77b48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dfe46d1b632bc94413194f086b1bc75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ee6bea62de427d78c15f4f903086628
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f08da6a0c06767407b972e7a073c451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9c27899387564989cc7e2571bf8fcc6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee70b8864b064611228bf0522e008ad8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c738d6e9672a3b50dea83d7011b180
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c68ec7523e889135d2c18643a32a538
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fed475f5a320ffda06a2f034e907b75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2349e25e0139e595513a2f268735c0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d13b67c8bf8067ab90b040a5148974
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b11ab2cfecab5b4ed0490fb9436a936
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24174098636d6eeff57a93ac8b2e68ec |
| publicationDate |
2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10837064-B2 |
| titleOfInvention |
Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma |
| abstract |
We found mutations of the R132 residue of isocitrate dehydrogenase 1 (IDH1) in the majority of grade II and III astrocytomas and oligodendrogliomas as well as in gliblastomas that develop from these lower grade lesions. Those tumors without mutations in IDH1 often had mutations at the analogous R172 residue of the closely related IDH2 gene. These findings have important implications for the pathogenesis and diagnosis of malignant gliomas. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11311527-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11738018-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11576906-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723905-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013733-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376246-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013734-B2 |
| priorityDate |
2008-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |