| abstract |
[PROBLEMS] To find a protein that interacts with the Zic2 protein, which plays an important role in neurogenesis, to elucidate the expression pattern and molecular function of the protein, and based on the obtained information, Use for medical purposes related to development and differentiation. [MEANS FOR SOLVING PROBLEMS] A marker for detecting neural stem cells or a marker for diagnosing brain tumors comprising a Rines protein comprising an amino acid sequence represented by a specific sequence interacting with a Zic2 protein or a polynucleotide encoding the protein, and a marker for detecting neural stem cells or a brain tumor Diagnostic kit. [Selection figure] None |