Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ddb9f3656270bc5410be3679322fead |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01184 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
filingDate |
2014-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbb36d5c1a81dafae8917a33f3429b47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce17cb5cf42b5921f4e485a73091794f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e11675be75fb51552595aafd0711697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc1c662120e9eb08db15181230b4eb52 |
publicationDate |
2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10294461-B2 |
titleOfInvention |
Modified carbonyl reducing enzyme and gene |
abstract |
An object of the present invention is to modify a wild-type enzyme that is less reactive in the presence of an organic solvent to provide altered carbonyl reductases having better reactivity in the presence of the organic solvent than the wild-type enzyme, and/or to provide transformants producing such reductases. The present inventors have found altered carbonyl reductases having better reactivity in the presence of an organic solvent than the wild-type enzyme, from among a mutant enzyme library prepared by randomly mutating the wild-type enzyme gene, thereby arriving at completion of the present invention. |
priorityDate |
2013-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |