http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2715679-C1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc8e1fce359ef4ee5bdc0add916dc5bd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
filingDate | 2019-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd5d7864e79957823f2e5840d6ad73a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfae306743c4e28d540c41fa02f08c09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31d4ba0b6df3765e695587c3f1978d94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40d176dfa2b1b1ee8b2430e3713a21fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b31bc81d9baf49abac57edb9320ac54a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c7f1767875d4debde4d47a5223faa68 |
publicationDate | 2020-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2715679-C1 |
titleOfInvention | Method of reducing pro-oxidant action of anticonvulsants in experiment |
abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to pharmacology and experimental medicine, and can be used to reduce pro-oxidant action of anticonvulsants in experiment. Method involves a daily intragastric introduction of an antiepileptic agent with a background of intraperitoneal administration of a succinate-containing preparation in dose of 100 mg/kg by succinate to laboratory animals. As a succinate-containing preparation, Reamberin is administered to rats 90 minutes before administration of Carbamazepine or valproic acid in dose of 150 mg/kg daily for 10 days.EFFECT: method provides reducing the pro-oxidant effect of anticonvulsants in experiment by reducing the content of peroxidation products in blood and liver of animals and increasing the activity of components of the antioxidant system under conditions of reducing Reamberin's course dose.2 cl, 4 tbl |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2792899-C1 |
priorityDate | 2019-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.