http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2714461-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a6b0bf6c3d9f24abfad81f059eb3aad |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate | 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7547e132d7e5ae5e66b981fb0b064ac4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d1e65cb69c2dac9d5dfc26bfdcbd2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7acf045d1d2cfdbb4a8f4c0faf4465a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271ac34f3a13a9590e07f110183d4d12 |
| publicationDate | 2020-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2714461-C1 |
| titleOfInvention | Method for assessing of scaffolds biocompatibility |
| abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, biology, veterinary science, pharmacology. Scaffold is implanted in the form of disc under the skin of rats. 7 days after the implantation, blood is sampled under general anesthesia. Blood is centrifuged to produce serum wherein concentration of Vascular Endothelium Growth Factor-A (VEGF) and syndecan-1 is determined. Obtained concentration ratio is calculated. For normalization of the ratio of concentrations of VEGF and syndecan-1, it is multiplied by a correction factor K, defined as the ratio of median values of syndecan-1 and VEGF concentrations in intact animals. If the normalized value of the ratio of the concentrations of VEGF and syndecan-1 does not exceed 2, then the absence of biocompatibility in the scaffold is stated.EFFECT: method enables reducing the time span of quantitative assessment of scaffold's biocompatibility with body tissues, as well as reducing labor intensity when assessing vascularization of biodegradable scaffolds.1 cl, 2 dwg, 1 tbl, 3 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2761266-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2743220-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2788283-C1 |
| priorityDate | 2019-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.