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filingDate 2016-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_327266297fff211b85bb5002524a1598
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publicationDate 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2663469-C2
titleOfInvention Hepatotrophic magnetic resonance contrast medium based on gadolinium chelate complex
abstract FIELD: medicine.SUBSTANCE: invention relates to the field of medicine, namely a hepatotropic magnetic resonance contrast medium, which is a microsphere whose shell is formed from a biodegradable polymer-polylactide, and the inner volume is filled with gel-forming polysaccharide – starch, and contains a water-soluble chelating complex based on gadolinium Gd– disodium salt of gadopentetic acid, the mass ratio of the components of the biodegradable polymer: gelling polysaccharide: gadolinium chelate complex is 32.3 % : 4.8 % : 62.9 % consequently.EFFECT: invention provides a higher content of gadolinium complex in the preparation, which allows to reduce the administered dose and to increase the contrast of the resulting image.1 cl, 2 dwg, 1 tbl, 5 ex
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