http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2577298-C1

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filingDate 2014-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3df40968010474f4e2f4f7aa0acf88dc
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publicationDate 2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2577298-C1
titleOfInvention Hepato-tropic magnetic resonance device
abstract FIELD: medicine. n SUBSTANCE: invention relates to contrast agents for increasing contrast of rendered image in MRI-diagnostics of liver and can be used in experimental and clinical studies. Haptotropic magnetic resonance contrast agent contains microspheres with diameter from 1 to 3 mcm, coating of which is made of biodegradable polymers of polylactides or polylactideglycolides, and the inner volume of the microspheres is filled with gel-forming polysaccharide containing water-soluble chelate complex on the basis of gadolinium Gd 3+ with a disodium salt of gadopentetic acid, with the following ratio of components: chelate complex of gadolinium: biodegradable polymer: gel-forming polysaccharide 1:2.0-2.4:0.3-0.5, respectively. n EFFECT: invention can be used in experimental and clinical studies. n 1 cl, 1 dwg
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2663469-C2
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