http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2655693-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00403e6a8eace565a27c4a449803b0bf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
| filingDate | 2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d29929b29482be516247269dc4475d15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a641f0496776fcddb9e29fc50e84fdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b4f117bebb2352ea0aa6ce17c8e6df8 |
| publicationDate | 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2655693-C1 |
| titleOfInvention | Method of obtaining the pharmaceutical substance based on iopromide |
| abstract | FIELD: medicine. n SUBSTANCE: group of inventions refers to medicine and relates to the process for the preparation of pharmaceutical substance based on iopromide, which includes the following steps: preparation of 1-amino-2,3-dihydroxypropane, preparation of 3-methylamino-1,2-propanediol, preparation of 5-nitroisophthalic acid, preparation of 5-nitroisophthalic acid dimethyl ester, preparation of 5-nitroisophthalic acid monomethyl ester, preparation of the solution of 3-[(2,3-dihydroxypropyl)carbamoyl]-5-nitrobenzoic acid, preparation of the solution of 3-amino-5-[(2,3-dihydroxypropyl)carbamoyl]-benzoic acid, preparation of 3-amino-5-[(2,3-dihydroxypropyl)carbamoyl]-2,4,6-triiodoisophthalic acid, 3-amino-5-{[2,3-bis (acetyloxy)propyl]carbamoyl}-2,4,6-triiodoisophthalic acid, preparation of 3-amino-5-{[2,3-bis(acetyloxy)propyl]carbamoyl-2,4,6-triiodoisophthalic acid chloride, preparation of 5-methoxyacetylamino-2,4,6-dichloride (2,3-diacetoxypropyl)-triiodizophthalic acid, preparation of [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide of 5-methoxyacetylamino-2,4,6-triiodizophthalic acid, preparation of iopromide. Group of inventions also refers to the use of iopromide, which is obtained by this method, as a pharmaceutical substance for the manufacturing of the medicament. n EFFECT: group of inventions ensures the production of high purity iopromide with the high output of the final product. n 12 cl, 2 ex |
| priorityDate | 2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.