| abstract |
FIELD: pharmacology. n SUBSTANCE: presented lactic acid bacterium contains a unit of polycistronic expression, the said polycistronic expression unit containing a gene endogenous to the said lactic acid bacterium (endogenous gene) and one or more genes exogenous to the said lactic acid bacterium (exogenous genes). The said endogenous gene and one or more exogenous genes are under transcriptional control of a promoter endogenous to the said lactic acid bacterium. n EFFECT: inventions provide high expression levels of heterologous proteins and can be used in medicine. n 52 cl, 23 dwg, 8 tbl, 16 ex |