http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2640250-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_697310d35f3489a5f69b2f17d11bbced |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-315 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5b593578ebee2a2ec7fca0cf8b55f79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46c95a00a30d710e7560f716ffbd4d96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b196820eaeb4099c1693d9c89d304170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_728168fb75d13593b6548fd99dbaa2ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b85049a9a8f659340c615859b163038b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3df5c35eb60bc775fc14e058651aa484 |
| publicationDate | 2017-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2640250-C2 |
| titleOfInvention | Method for introgression of pathogenic streptococcus genes in chromosomal dna of probiotic strain of enterococcus faecium l3 for expression in piles |
| abstract | FIELD: biotechnology. n SUBSTANCE: invention relates to a method of producing a live vaccine on the basis of biologically active strain Enterococcus faecium L3 due to the itrogression of the antigen of a clinically relevant pathogenic microorganism into the structure of the strain piles. This method involves producing a fusion gene of entF-bac, consisting of two separate gene fragments of probiotic E.faecium L3 and gene fragment bac and having a nucleotide sequence, shown in fig. 7a, its cloning and detection of bacterial clones expressing the desired protein in piles. The invention also relates to recombinant plasmid DNA pentF-bac. The real DNA pentF-bac is designed to create a live vaccine based on the biologically active strain of E. faecium L3. This pentF-bac DNA is a suicide plasmid pT7ERMB, at BamHI and KpnI sites of which the sequence of entF-bac fusion gene DNA is inserted. The present invention also relates to a vaccine preparation of E.faecium L3 Bac+. This vaccine preparation is prepared by electroporation of E. faecium L3 of plasmid pentF-bac DNA. n EFFECT: invention allows for the production of a live vaccine based on the biologically active strain. n 3 cl, 9 dwg, 1 tbl, 5 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2776479-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2777061-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2701733-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2782529-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2745626-C1 |
| priorityDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.