http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2638785-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5205c25b782ff85e96fda9512faca381 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2016-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_688981fa256aadb93bc8c866004a6182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2248f88d1ece8616a579bbb3f705c548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09d408483d7bfffd9182d583741ec7d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d327e919b4e2dec7593070b9fd2d3160 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6622fd196691f25ceb8a6c5f240218c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caefdafc3544f477a99c5c632ac499cb |
publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2638785-C1 |
titleOfInvention | Method for prediction of risk of severe preeclampsia development |
abstract | FIELD: medicine. n SUBSTANCE: method involves isolation of DNA from peripheral venous blood, analysis of MMP-8 (rs1320632) gene polymorphism in combination with other predictors of development of this pregnancy pathology. Risk of severe preeclampsia development is predicted according to the equations of linear discriminant function: y 1 =-14.767+ 2.914x 1 +1.439x 2 +0.222x 3 +14.345x 4 , y 2 =-2.228+2.305x 1 -0.718x 2 +1.888x 3 -0.254x 4 , where x 1 - is genetic version at the MMP-8 (rs1320632) locus (AA - 1; AG or GG - 0), x 2 is presence of preeclampsia in relatives (1 - yes, 0 - no), x 3 is presence of sexually transmitted diseases (1 - yes, 0 - no), x 4 is presence of gynecological pathologies in the anamnesis (1 - yes, 0 - no), in the event that the value of y 1 is greater than y 2 . n EFFECT: effective implementation of therapeutic and preventive measures to prevent pregnancy pathology. n 3 ex, 2 dwg |
priorityDate | 2016-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.