http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2596829-C2

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filingDate 2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92815b0869a943abdb1301ef1a5571a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbc4b5a6f3ad022a988780aa8c1cf976
publicationDate 2016-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2596829-C2
titleOfInvention Obtaining derivative of 1-amino-3-hydroxycyclobutane-1-carboxylic acid
abstract FIELD: chemistry. n SUBSTANCE: invention relates to method of producing compounds with IVa formula which can be used as precursors for producing amino acids marked with radioisotopes for use in positron emission tomography. According to disclosed method compound of IVa formula is obtained in amount of 100 g or more from the compound of IIIa formula where pH of reaction medium containing compound of IIIa formula is brought to 2.0-5.0 and hydrogenolysis of X group is performed using wet catalyst selected from platinum group metals. R in IVa and IIIa formulae denotes alkyl group with 1-5 carbon atoms, Y denotes protective group of amine and X denotes protective group of alcohol. n EFFECT: method enables safe bring of reaction to completion when implemented in large-scale. n 10 cl, 1 tbl, 1 ex
priorityDate 2011-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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