http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2009128664-A
Outgoing Links
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C219-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G21H5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01T1-161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-28 |
filingDate | 2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2011-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2009128664-A |
titleOfInvention | THE PROCESS OF OBTAINING PREDUCTIVE COMPOUNDS FOR RADIOACTIVE HALOGEN-labeled COMPOUNDS |
abstract | 1. A method of obtaining a precursor compound of a radioactive compound labeled with fluorine, which includes! stage of interaction, providing conditions for the interaction of a solution containing a substance with the following chemical formula (1)! ! where R1 is a protective group of a carboxyl group, and R2 is a protective group of an amino group together with a base and a compound reactive with the OH group of a compound with the chemical formula (1), and the protective group becomes a leaving group,! as well as ! the stage of purification of the reaction solution obtained at the stage of interaction to obtain an almost individual stereoisomer of a substance with the following chemical formula (2)! ! where R1 is a protecting group of a carboxyl group, R2 is a protecting group of an amino group, and R3 is a leaving group. ! 2. The production method according to claim 1, in which the compound reacting with the OH group of the compound with the chemical formula (1), becoming a leaving group at the stage of interaction, is one or more compounds selected from the group consisting of straight-chain alkyl sulfonic acid or a branched chain of 1-10 carbon atoms, a straight or branched chain haloalkylsulfonic acid of 1-9 carbon atoms, aromatic sulfonic acid and aromatic sulfonic acid chloride. ! 3. The production method according to claim 2, in which the alkyl sulfonic acid is methanesulfonic acid. !four. The production method according to claim 2, wherein the haloalkyl sulfonic acid is trifluoromethanesulfonic acid. ! 5. The production method according to claim 2, in which the aromatic sulfonic acid is toluenesulfonic acid |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2596829-C2 |
priorityDate | 2006-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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