http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2557554-C1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd0f87e661b4360800b6e8a2fd26b458 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-23 |
filingDate | 2014-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3ebb2e3c68dbf1a5b95d6baebb7438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d29632451db3705d957ad20a8737fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b2888aff2087abef3f3e771ce332d92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_244cdc3282b2951db60a2881a9630b88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64d7d574fbfb5263ce583e626a389039 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b90a78b9aced10a622ab2fa9e127a7c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1b39f592449a5968becabcd1bdcac83 |
publicationDate | 2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2557554-C1 |
titleOfInvention | Indolocarbazole derivative blocking tumour vasculogenic mimicry |
abstract | FIELD: medicine. n SUBSTANCE: invention refers to indolocarbazole derivatives blocking tumour vasculogenic mimicry and applicable in medicine, of general formula I: , wherein Gly is pentose and hexose residues, R represents an amino group of 6-amino-12-(α-L-arabinopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; a formamido group of 6-formamido-12-(β-D-xylopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; an oxylethylamino group of 6-(2-oxyethyl)amino-12-(α-L-arabinopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; a cyanoethylamino group of 6-(2-cyanoethyl)amino-12-(β-D-xylopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione and 6-(2-cyanoethyl)amino-12-(β-D-galactopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; a picolinamido group of 6-picolinamido-12-(β-D-xylopyranosyl)indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione. n EFFECT: there are presented new compounds with the cytotoxic and antiangiogenic properties active with respect to HCT-116 colon cancer and Mel Kor melanoma. n 6 ex, 1 tbl, 3 dwg |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2667906-C1 |
priorityDate | 2014-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.