http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2495020-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff346a4b8595551f1fdd6153af5a1907 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-44 |
| filingDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1d99558b5f6c4493a67efe87e25c38f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b291ea6642d68246f7761faa7131406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_815deba08a9a22b4bc7d9082b9436861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_162e4f04dace7e81239bb5941ff03714 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b9436f8e1324ef66f9f5d8c0ba4aa2f |
| publicationDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2495020-C1 |
| titleOfInvention | Method of producing 2-(2-amino)alkyladamantanes |
| abstract | FIELD: chemistry. n SUBSTANCE: invention relates to chemistry of adamantane derivatives, particularly an improved method of producing 2-(2-amino)alkyladamantanes of general formula (I), which can be of interest as intermediate products in synthesis of certain biologically active substances. The method of producing 2-(2-amino)alkyladamantanes of general formula (I): , where X=H, OH; R=H, CH 3 , C 2 H 5 , involves reducing 2-adamantylene acetonitrile with active hydrogen formed by reacting potassium hydroxide with aluminium contained in a nickel-aluminium (50/50) Raney alloy, with molar ratio of nitrile to hydrogen of 1:5-10. Reduction is carried out in a water-tetrahydrofuran medium. n EFFECT: method increases technological effectiveness of synthesis by changing conditions for implementing the method, enables to obtain a wider range of 2-(2-amino)alkyladamantane derivatives and also increases output of products to 90-96% and purity thereof. n 6 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2605698-C1 |
| priorityDate | 2012-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.