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grantDate 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b86e554574d4502e07bb538233019e26
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publicationDate 2013-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2485502-C1
titleOfInvention Method for assessing morphofunctional status of human thrombocytes
abstract FIELD: medicine. n SUBSTANCE: sampled blood, or plasma, or thrombocyte concentrate is stained in a micro-tube with tripaflavine and acridine orange, and a fluorescence microscope is used to count thrombocyte granules, to measure a light intensity of 100-200 vitally stained cells; the light intensities are summed and divided on the thrombocyte count examined to calculate an average thrombocyte light intensity to be expressed in foot-candles per 1 cell relevant to one point characterising morphofunctional thrombocyte activity (MFAT). Further, the preparation with vitally stained thrombocytes is placed in a thermostat; a fluorescence microscope is used to count by spread-eagle thrombocytes with projecting granules, divided by total cell count analysed and expressed in %, wherein one percent is relevant to one point characterising thrombocyte adhesive activity (TAA). Then total MFAT and TAAT show the morphofunctional status of thrombocytes. n EFFECT: method provides an objective assessment of the morphofunctional status of human thrombocytes. n 6 dwg, 6 tbl, 3 ex
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