http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2374258-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10efc646a4dd605c2f09c493718f5b81 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 |
| filingDate | 2008-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d740b3ec568d561dbd030fc467296a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37d49129b641135eced16710a442a812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93a5089ad44a0f9c581c7d01b5e1b8e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8df1463835a11bf83ddb1323625c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef5ce2c6618004b32d61f22b70550dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cf579b8fea7ebe727262ec86adbced4 |
| publicationDate | 2009-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2374258-C1 |
| titleOfInvention | Method of producing n,n-dialkyl,n'-acyl-(acyldialkoxyphosphoryl)ethaneamidines |
| abstract | FIELD: chemistry. n SUBSTANCE: present invention relates to a method of producing N,N-dialkyl, N'-acyl-(acyldialkoxyphosphoryl)ethaneamidines and can be used in synthesis of biologically active compounds. The proposed method of producing N,N-dialkyl, N'-acyl-(acyldialkoxyphosphoryl)-ethaneamidines of formula , where R 1 =C 3 -C 4 -alkyl or isoalkyl; R 2 =CH 3 , C 6 H 5 ; R 3 =C 3 -C 3 -alkyl; R 4 =CH 3 , C 6 H 5 ; involves reacting C-phosphorylated acetamidines with sodium with subsequent acylation of the obtained sodium derivative with acid halides such as acetyl bromide or chloride and benzoyl chloride, in a dioxane medium at molar ratio sodium: C-phosphorylated acetamidine: acid halide = 1:1:1÷1.1, respectively, and temperature between 20 and 50°C. n EFFECT: design of a new method of producing new N,N-dialkyl, N'-acyl-(acyldialkoxyphosphoryl)ethaneamidines with high output of 80 to 86%. n 1 cl, 5 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2529199-C1 |
| priorityDate | 2008-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.