| abstract |
FIELD: chemistry. n SUBSTANCE: compounds of the invention have chemokine antagonistic properties and can be applied in treatment of immunoinflammatory diseases, such as atherosclerosis, allergy diseases. In general formula (I) R 1 is hydrogen atom, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkoxyl, cyclopropylmethoxy group, (C 1 -C 4 )-alkylthio group; R 2 is halogen atom, (C 1 -C 8 )-alkyl, perfluoro-(C 1 -C 4 )-alkyl, (C 3 -C 10 )-cycloalkyl, phenyl, (C 1 -C 8 )-alkoxyl, values of the other radicals are indicated in the claim of the invention. n EFFECT: improved properties. n 14 cl, 7 tbl, 20 dwg, 17 ex |