| abstract |
FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to diphenyl heterocyclic compounds of the formula (I) where Het means fragment taken among the group consisting of (A) , (B) , (C) , (D) , (E) , (F) , (G) , (H) . These compounds are modulators of calcium-activated potassium channels of high conductivity and therefore they can be used for protection of nerve cells, especially in treatment and prophylaxis of patients with ischemia attack. Invention relates to also method of treatment of patients with new compounds and to pharmaceutical composition containing these compounds. EFFECT: improved method of treatment, valuable medicinal properties. 19 cl, 1 tbl, 146 ex |