http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LT-5706-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_671f66016a66b2a74bd3b52b51cc90db |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91011 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate | 2009-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48cbf2f79c88f5a67fb9c4ebfdb6cc83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95e07edca2f8da607046b9561e516ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d688124ff5b4f6897e5df24ada2ea74 |
| publicationDate | 2011-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | LT-5706-B |
| titleOfInvention | Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases |
| abstract | The present invention relates to targeted conversion of alpha-hydroxyalkylatedresidues in biomolecules in the presence of a directing methyltransferase, namely, to targeted removal of the alpha-hydoxyalkyl moieties to give unmodified residues, or targeted derivatization of the alpha-hydroxyalkyl groups by covalent coupling of non-cofactor compounds represented by formula HQ-LX, wherein X represents a functional group or a reporter group attached via a linker moiety L, and QH is selected from HS-, HSe-, HO- H2N-, HN3 or HCN in the presence of a directing methyltransferase. Further development of the method of targeted conversion comprises methods for targeted labeling a biomolecule and methos for detecting hydroxymethylated target sites in a biomolecule according to the present invention.รก |
| priorityDate | 2009-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.