http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210144121-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 |
| filingDate | 2020-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210144121-A |
| titleOfInvention | Artificial scaffold for corneal endothelial cell transplantation, manufacturing method thereof, and ultra-thin descemet stripping endothelial graft using the same |
| abstract | The present invention relates to a method for tissue engineering manufacturing an artificial scaffold for corneal endothelial cell transplantation, and to a super-thin Descemet's membrane detachment corneal endothelial plate graft in which cells are transplanted into the scaffold prepared by the above method and recellularized. The method for manufacturing an artificial scaffold for corneal endothelial cell transplantation of the present invention can produce a scaffold with excellent transparency and an ultra-thin thickness through an optimal decellularization process. In addition, the scaffold prepared by the method of the present invention has excellent morphological stability and can provide an appropriate microenvironment for cell survival and differentiation. It can show a high survival rate as well as an even distribution of cells. In addition, the Descemet's membrane detachment corneal endothelial plate graft, which is recellularized by transplanting corneal endothelial cells into the scaffold of the present invention, can maintain an ultra-thin form of 90 to 120 μm in thickness with high transparency, and heterogeneity capable of causing immune rejection Since it does not contain substances, it can be usefully used for corneal endothelial cell transplantation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023163468-A1 |
| priorityDate | 2020-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.