abstract |
The present invention relates to a 1,2,3-triazole derivative compound having heat shock protein 90 (HSP90) inhibitory activity, an optical isomer thereof, and a pharmaceutically acceptable salt thereof; their use for the manufacture of a medicament for treatment; treatment methods using them; pharmaceutical compositions containing them; and to a method for their preparation. The compound represented by the formula (I) of the present invention, its optical isomer, or a pharmaceutically acceptable salt thereof can selectively inhibit HSP90, so that the preventive or therapeutic effect on HSP90 activity-related diseases is remarkably excellent. |