http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210063310-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e078e4e4626c5c52bf207640881d8eaf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate | 2021-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec47b7227237c3ea13a2132902efbc5 |
| publicationDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20210063310-A |
| titleOfInvention | Method for production of glucagon-like peptide-2 or analogues with groes pusion |
| abstract | One embodiment of the present invention relates to a fusion tag, a fusion polypeptide comprising the fusion tag and glucagon-like peptide-2 or an analog thereof. When the novel fusion tag according to the present invention is used, the yield of glucagon-like peptide-2 or an analog thereof can be improved compared to the conventional fusion tag. In particular, it is useful when a glucagon-like peptide-2 or an analog thereof having a relatively small molecular weight and easily degraded amino terminus is prepared using genetic recombination technology. In addition, the fusion polypeptide comprising the fusion tag according to an embodiment of the present invention is protected from proteolytic enzymes of the host cell by inducing expression in the form of an inclusion body in the host cell, thereby stably glucagon-like peptide-2 or its It has the advantage of being able to produce analogues. Therefore, it is possible to provide a method for producing glucagon-like peptide-2 or an analog thereof, which has improved stability and yield compared to the case of using a conventional fusion tag. |
| priorityDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 628.