| abstract |
a) providing a eukaryotic cell comprising a nucleic acid encoding an immunoglobulin, b) culturing the eukaryotic cell in a culture medium, wherein the amount of usable glucose in the culture medium per unit of time is kept constant, A method for producing an immunoglobulin comprising the step of being limited to less than 80% of the amount that can be used maximally by cells in the culture medium per unit of time, and c) recovering the immunoglobulin from the culture. It is reported herein. |