abstract |
(57) [Summary] [Structure] When a glycoprotein is produced by culturing animal cells in a medium, the type of sugar chain of the glycoprotein produced by changing the sugar composition or sugar concentration in the medium or A method of modifying the molecular weight. [Effects] The sugar chain of a glycoprotein can be modified by changing the sugar composition and sugar concentration in the medium, and glycoproteins having different properties can be arbitrarily obtained by a simple method. |