| abstract |
The present invention relates to a compound having high selectivity to tau aggregates and a method for preparing the same, a tau target fluorescent probe containing the compound, a composition for detecting tau fibroprotein comprising the fluorescent probe as an active ingredient, and diagnosis of tauopathy of the composition It is about the use. In particular, since the compound of the present invention does not bind to amyloid beta protein and has high selectivity to tau aggregates, which are specifically reported as the etiology of the initial state of tauopathy, tau fibers for early diagnosis of tauopathies including Alzheimer's disease It can be usefully utilized as a fluorescent detector for protein detection. |