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filingDate 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20200112746-A
titleOfInvention Novel thermosensitive cellulose based hydrogel for post-surgical peritoneal adhesion prevention and preparation method thereof
abstract The manufacturing method of the anti-adhesion temperature-sensitive cellulose-based hydrogel according to the present invention includes polyethylene glycol, tempo-oxidation medium-nanocellulose, methyl cellulose, and hyaluronic acid. acid) to prepare a mixture; Stirring the mixture; And adding sodium chloride to the stirred mixture to gel. When the anti-adhesion temperature-sensitive cellulose-based hydrogel and its manufacturing method are used in the present invention, a stable gel matrix is formed without a crosslinking agent and an excellent anti-adhesion effect is shown. In addition, the present invention has the advantage of providing an excellent anti-adhesion hydrogel without excellent biodegradability, mechanical stability, heat sensitivity and cytotoxicity.
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