http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190001742-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb65ab1b41c2067a40270436dc55a429 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-1015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-107 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2017-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4675cb949ee60fb543a1188345ca4df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dd19fa394cb2f066a047cf32d5b335d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec78934092e4ac0cee775e01d1f6685f |
publicationDate | 2019-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20190001742-A |
titleOfInvention | Target nucleic acids detection method using quantum dot for dispersed light |
abstract | The present invention relates to a method for detecting a target nucleic acid based on the fluorescence characteristic of a fluorescent dye that changes state when a detecting probe is hybridized to a target nucleic acid, By excitation, the reagent for detecting the target nucleic acid can be easily prepared and used without bioconjugation of the quantum dots, and the fluorescent light of the fluorescent dye to be excited by the quantum dots can be prevented from interfering with each other, The present invention relates to a method for detecting a target nucleic acid which can accurately detect a target nucleic acid by analyzing a target nucleic acid in the presence of a quantum dot, A hybridization step of inducing a change in the state of the fluorescent dye; Detecting a target nucleic acid by detecting fluorescence light of a fluorescent dye that receives emission light of a quantum dot serving as a dispersion light source by exciting scattered quantum dots; . The research related to the present invention was carried out with the support of the core material technology development business of the Ministry of Industry and Commerce (development of PNA-nanohybrid fusion material and molecular diagnostic system for cancer gene diagnosis at the level of femtomole, Project No. 10047831). In addition, a verification test applying the target nucleic acid detection method according to the present invention to actual clinical samples was carried out by receiving a clinical sample from the material-resource bank of Incheon St. Mary's Hospital. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020190063-A1 |
priorityDate | 2017-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.