| abstract |
The present invention provides a compound of formula I, or a stereoisomer, tautomer thereof, or a pharmaceutically acceptable salt thereof. These compounds are selective inhibitors of factor XIa or dual inhibitors of FXIa and plasma calicaine. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of treating thromboembolic and / or inflammatory disorders therewith. (I) Wherein all variables are as defined herein. |