Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ede47b877b6df9c8d0c494cd66f45ae8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48169 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
filingDate |
2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53e723d6b990f817bc49ec8a25502861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b777f78f460e35b8aa788b15b2e3561c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2da340f371e5aa7530e62eabf5cdf6c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eedbeb369bbfef1328808600fc82ba5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b4571c219a13d166c7d80574a7ad5ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1723c2a151d872c4c3ab387b547c9a4e |
publicationDate |
2016-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20160123415-A |
titleOfInvention |
Method of producing a tumor specific siRNA delivery system containing gold nano particles |
abstract |
The present invention relates to a method for preparing an siRNA delivery vehicle, and more particularly, to a method for preparing a siRNA delivery system, comprising: a first step of reacting a cationic polymer and an siRNA to form a complex of a cationic polymer and siRNA; A second step of reacting the complex with an aqueous chloride solution; And a third step of reacting the reaction product of the second step with polyethyleneglycolated hyaluronic acid. The present invention also relates to a method for producing a cancer cell-specific siRNA delivery system. A first layer comprising a complex of cationic polymer and siRNA, and gold nanoparticles; And a second layer modified on the surface of the first layer and comprising polyethylene glycolized hyaluronic acid. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112143490-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200085348-A |
priorityDate |
2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |