http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160123415-A

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filingDate 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2016-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20160123415-A
titleOfInvention Method of producing a tumor specific siRNA delivery system containing gold nano particles
abstract The present invention relates to a method for preparing an siRNA delivery vehicle, and more particularly, to a method for preparing a siRNA delivery system, comprising: a first step of reacting a cationic polymer and an siRNA to form a complex of a cationic polymer and siRNA; A second step of reacting the complex with an aqueous chloride solution; And a third step of reacting the reaction product of the second step with polyethyleneglycolated hyaluronic acid. The present invention also relates to a method for producing a cancer cell-specific siRNA delivery system. A first layer comprising a complex of cationic polymer and siRNA, and gold nanoparticles; And a second layer modified on the surface of the first layer and comprising polyethylene glycolized hyaluronic acid.
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type http://data.epo.org/linked-data/def/patent/Publication

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