| abstract |
Methods and systems for sensor calibration and sensor glucose (SG) fusion are advantageously utilized to improve the accuracy and reliability of orthogonal redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors can be accomplished through fixed-offset and / or dynamic regression methodologies, for example, depending on sensor stability and Isig-ratio pair correlation. For SG fusion, respective integrity checks can be performed on the SG values from the optical and electrochemical sensors, and the SG values are calibrated when the integrity checks are passed. Integrity testing may include examining sensitivity loss, noise, and drift. If integrity checks fail, in-line sensor mapping between electrochemistry and optical sensors may be performed prior to calibration. The electrochemistry and optical SG values can be weighted (as a function of the overall reliability index (RI) of each sensor) and the weighted SGs are combined to obtain a single, fused SG value. |