| abstract |
The present invention relates to a fusion protein in which hGH is bound to a skin permeation promoting peptide, a polynucleotide encoding the fusion protein, a cosmetic composition for skin improvement comprising the fusion protein, and a pharmaceutical composition for external application for skin comprising the fusion protein will be. The fusion protein of the present invention binds hGH to a skin permeation enhancing peptide, thereby maintaining or enhancing the ability to synthesize a substance showing beneficial effects such as collagen and elastin, and also significantly improving skin permeability and skin retention , A functional cosmetic composition, and a pharmaceutical composition for external application for skin. |