abstract |
The present invention relates to a method for producing dedifferentiated pluripotent stem cells from somatic cells derived from human using a fusion protein of a reprogramming inducing factor and a cell permeable peptide (CPP), a method for producing a pluripotent pluripotent stem cell and a cell permeable peptide Fusion proteins. According to the present invention, in inducing the differentiation of somatic cells, it is highly possible to eliminate the existing viral peptide transporter, thereby maximizing the effect of the dedifferentiation inducing transcription factor and producing highly efficient pluripotent stem cells have. |