http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20130094498-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-137 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate | 2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_937e7d907d9705fa2f0cfa81eedbd4e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4871d9e16fe23f3544af724532f5ca4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c4180341daff69b74390e7527c03ddd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53b8b64973429fb2ab794f6ddc00c5d |
| publicationDate | 2013-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20130094498-A |
| titleOfInvention | Target Gene or Mutation Detection Method Using Ligase and Cleavage Amplification |
| abstract | The present invention relates to a method for detecting a target gene or a mutation thereof, and more specifically, (a) performing a polymerase chain reaction; (b) Ligase reaction using the first and second probes complementarily binding to the 5 'region and the 3' region of the target gene with respect to the target gene amplification product of step (a), respectively Performing; (c) adding a mixed solution of a cleavage amplification primer, a cleavage enzyme and a polymerase to the reaction product of step (b) and performing a nicking amplification; And (d) relates to a method for detecting a target gene or a mutation thereof comprising the step of confirming the presence or absence of the DNA fragment amplified in the reaction product of step (c). The target gene or a method for detecting a mutation thereof according to the present invention is excellent in sensitivity, specificity and reproducibility as well as having a large number of DNA fragments of any short length. Simultaneous and accurate analysis can be used as a platform for biosensors for on-site diagnosis, as well as for the prevention of genetic diseases, early diagnosis and the development and prescription of personalized medicines. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180093636-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102138183-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220017381-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190081271-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466312-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019132626-A1 |
| priorityDate | 2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.