http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120132594-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20120132594-A |
| titleOfInvention | Cancer specific gene therapy through regulation with microRA |
| abstract | The present invention relates to a gene therapeutic agent having cancer-specific anticancer and diagnostic effects by controlling the expression of expression vectors in the post-transcriptional process using microRNA. Using the present invention, by repeatedly including the target sequence for a particular microRNA that is not expressed in cancer cells in the 3 'UTR region of the ribozyme, the expression of the expression vector is regulated in the post-transcriptional process, thereby preventing cytotoxicity in normal cells. Significantly reduce side effects and reinforce the cancer specificity compared to the prior art, there is an advantage of excellent cancer treatment efficacy by introducing a therapeutic gene specifically for cancer cells. In addition, it can be used as a diagnostic agent and an in vivo imaging agent that can diagnose cancer progress specifically cancer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3733213-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020146033-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160101806-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111607610-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230073600-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016126071-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016052851-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557140-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160038674-A |
| priorityDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 558.